I love Ben Godfre's new, rougher look wth chest and facial hair. Thanks for sharing.
Bob
On Fri, Jul 20, 2012 at 1:54 AM, Jake West <jakewest_tn@yahoo.com> wrote:
Model Wars-Jul 20, 2012- / Health-News-PICS
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Consider joining:Members should join the Re-Elect President Barack Obama Group . (Health Care & Gay Rights, Gay Marriage, Repeal DOMA, Don't Ask & Don't Tell).... Osama Bin Laden killed (May 1, 2011)! President Obama was totally involved and viewed the entire operation in real time. Pres. Obama personally recongnizes Same-Sex Marriage! Meamwhile, Mitt Romney is an Anti-gay High School Bully that cut off the long hair of a gay boy who cried as Mitt Romney laughed as he sat on top of the boy and cut off his hair, against the boy's will. Others in Romney's gang, helped to hold down the boy per Romney's orders as Romney did the cutting with a large pair of scissors. As adults, these guys came out and confessed what they did, confronted the boy who died as an adult and apologized. They admitted that Romney was the boy who was in charge of the gang and cut the hair off the boy! Not one person has stated otherwise! So it stands, Romney is an anti-gay High-school Bully for life! Today, this is a criminal offense as he would be guilty of a antI-gay hate crime with the use of a weopon that can kill, punnishable with a prison sentence!
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Science Blog / July 19, 2012
A new study by scientists on the Florida campus of The Scripps Research Institute shows, in cell culture, a natural compound can virtually eliminate human immunodeficiency virus (HIV) in infected cells. The compound defines a novel class of HIV anti-viral drugs endowed with the capacity to repress viral replication in acutely and chronically infected cells.
The HIV/AIDS pandemic continues to affect 34 million individuals worldwide, including more than 3 million children, according to the World Health Organization. Current treatment involves the use of several antiretroviral drugs, termed Highly Active Antiretroviral Therapy (HAART), which can extend the life expectancy of HIV-positive individuals and decrease viral load without, however, eradicating the virus.
"We know that there are reservoirs of HIV that aren't being eliminated by current treatment and that keep replenishing the infection," said Susana Valente, a Scripps Research biologist who led the study. "Viral production from these cellular reservoirs that harbor an integrated viral genome is not affected by current antiretroviral drugs, which only stop novel rounds of infection. The compound in the current study virtually eliminates all viral replication from already-infected cells where HIV hides."
The new study, published in the July 20, 2012 issue of the journal Cell Host and Microbe, focused on a medically promising compound known as Cortistatin A. This natural product was isolated in 2006 from a marine sponge, Corticium simplex, discovered more than 100 years ago. In 2008, Scripps Research chemist Phil Baran and his team won the global race to synthesize the compound, presenting an efficient and economical method.
In the new study, Valente and her colleagues collaborated with the Baran lab, using a synthetic version of the compound, didehydro-Cortistatin A, to study the compound's effect on two strains of HIV. The strains were HIV-1, the most common form of the virus, and HIV-2, which is concentrated in West Africa and some parts of Europe.
The results showed that the compound reduced viral production by 99.7 percent from primary CD4+T cells (a type of immune cell) isolated from patients without levels of the virus in their bloodstream and who had been under HAART treatment for a long period of time. When the compound was added to other antiviral treatments, it further reduced by 20 percent viral replication from CD4+T cells isolated from patients with detectable amounts of virus in their bloodstreams.
The inhibitor works by binding tightly to the viral protein known as Tat, a potent activator of HIV gene expression, effectively preventing the virus from replicating even at miniscule concentrations—making it the most potent anti-Tat inhibitor described to date, Valente said.
Another interesting feature of this compound is that withdrawal of the drug from cell culture does not result in virus rebound, which is normally observed with other antiretrovirals.
While most antiretroviral compounds block only new infections, didehydro-Cortistatin A reduces viral replication from already-infected cells, potentially limiting cell-to-cell transmission.
The new inhibitor already has a drug-like structure, is effective at very low concentrations, and has no toxicity associated with it, at least at the cellular level, the study noted.
The first author of the study "Potent Suppression of Tat-dependent HIV Transcription by didehydro-Cortistatin A" is Guillaume Mousseau of Scripps Research. In addition to Valente and Baran, other authors include Mark A. Clementz, Wendy N. Bakeman, Nisha Nagarsheth, Michael Cameron, and Jun Shi of Scripps Research; and Rémi Fromentin and Nicolas Chomont of the Vaccine and Gene Therapy Institute.
The study was supported by the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and the Landenberger Foundation.Take Action:
And Now, Our War of the Fittest!
This group is called "Peckers Pics." The English - slang definition of "pecker" is to pluck at the truth. Therefore, we peck at items such as Gay Men's Health, Male Fitness, Gay (LGBT) Politics & Issues. In this section you may peck at each photo in order to decide the winner of the "war of the fittest!" Whereas, you should select the "Male Athlete" that may inspire you to exercise and "get fit!" Warning: This may stoke you!Your participation in discussion of health / news articles - appearing in this message is greatly appreciated!Urgent Notice: Our ObamaBiden2008 Group works hand - in - hand with Peckers PICS (Both groups were co-created to work with each-other). To prevent duplication of articles and questions, all members of this group are urgently recommended to join ObamaBiden2008 . We have the LGBT boycott list and discuss end of DADT, etc... There are 3 gay teen suicides in the USA - daily! There are Hate crimes against gay people. There are gay people who are fired over their sexual identity. There are gay people who died for our cause! These groups are focused towards Yahoo Members who sincerely care about LGBT rights and are interested in Gay Men's Health! Most important, we have a most critical election in 2012 that shall determine the future of LGBT rights and our health care (as many suffer from pre-existing illness)! Please Join Now!Join the group @ http://sports.groups.yahoo.com/group/JakeWest/joinIts my finest group!Why have you not joined?Members note: "Best blog ever!My personal PICS!My Lover's PICS!Pics of my favorite men!The story of my life!The truth of everything you wanted to know and never dreamed of!
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"Every gay and lesbian person who has been lucky enough to survive the turmoil of growing up is a survivor. Survivors always have an obligation to those who will face the same challenges."
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To join the Obama group please click (or copy and paste the link into your browser) @ http://groups.yahoo.com/group/ObamaBiden2008/join
Thank you!
"Every gay and lesbian person who has been lucky enough to survive the turmoil of growing up is a survivor. Survivors always have an obligation to those who will face the same challenges."
...Jake (Moderator)
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