Friday, October 14, 2011

[Peckers_Pics] Male/Gay Health-Discussion-PICS Model Wars-Oct 15, 2011-Boycott Georgia-Trump-TARGET-FOX NEWS-Salvation Army



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Health - Wellness - Exercise - Reflections:
HIV Integrase Inhibitors Isentress and Dolutegravir Continue to Show Well

Oct 14, 2011 - AIDSMeds

Merck's integrase inhibitor Isentress (raltegravir) continues to perform well, compared with Sustiva (efavirenz), after four years in people living with HIV starting therapy for the first time in the company's STARTMRK clinical trial. For those who do develop HIV drug resistance to Isentress, the experimental integrase inhibitor dolutegravir (S/GSK-572) showed promise as a second-line treatment option in ViiV Healthcare's VIKING study. Both sets of study conclusions were reported Thursday, October 13, at the 13th European AIDS Conference in Belgrade, Serbia.
 
After 192 weeks of treatment involving Isentress plus Truvada (tenofovir plus emtricitabine), according to the strictest data analysis performed by Jürgen Rockstroh, MD, of the University of Bonn in Bonn-Venusberg, Germany, and his STARTMRK colleagues, about 76 percent of Isentress-treated patients had undetectable viral loads (below 50 copies), compared with 67 percent of patients in the Sustiva group.
 
Though Isentress appeared to do a better job of maintaining undetectable viral loads throughout the prolonged follow-up period, the study was not designed to determine the statistical superiority of one regimen over another.
 
As for patients with HIV resistance to Isentress--and, most likely, to Gilead's experimental integrase inhibitor elvitegravir--dolutegravir reduced viral load to below 50 copies in about 75 percent of patients treated for 24 weeks. These findings, which come from a second group of patients using 50 milligrams (mg) of the drug twice daily, are superior to those of an initial group of patients in the VIKING study involving once-daily dosing of the drug. Compared with those in VIKING cohort II, undetectable viral loads after 24 weeks were documented in only 41 percent of those in VIKING cohort I.
 
Three-year follow-up data from STARTMRK were recently published in the October 15 issue of Clinical Infectious Diseases. The four-year follow-up data are similar, in that they conclude that a regimen of twice-daily Isentress plus once-daily Truvada appears to work just as well as once-daily Sustiva plus Truvada--usually taken together as Atripla--but with fewer blood lipid problems.
 
Of note, the four-year follow-up data from STARTMRK suggest that Isentress-based therapy may have an immunologic edge over Sustiva-based treatment. According to the data shared by Rockstroh's group in Belgrade, CD4 counts increased, on average, by 360 cells in the Isentress group, compared with 300 cells in the Sustiva group. But here, too, a statistical comparison to determine superiority was not possible.
 
Preliminary 11-day study results from VIKING cohort II were reported at the 18th Conference on Retroviruses and Opportunistic Infections in Boston, earlier this year, with 24-week follow-up data reported by Vincent Soriano, MD, of Hospital King Carlos in Madrid and his colleagues in Belgrade.
 
Compared with the lackluster virologic response using once-daily dolutegravir documented in VIKING cohort 1, Soriano confirmed that twice-daily dosing made a significant difference. Based on these results, ViiV's Phase III clinical trial program will further explore the safety and efficacy of twice-daily dolutegravir in people living with HIV with evidence of resistance to Isentress and elvitegravir. For patients starting therapy for the first time or with no integrase inhibitor experience, once-daily dosing continues to be a possibility and is being evaluated in clinical trials.
 
Data from VIKING cohort II suggest that treatment responses to dolutegravir, even when twice-daily dosing is used, will depend on the actual integrase mutations that occur during treatment with first-generation integrase inhibitors. And much like other experimental agents that show promise against drug-resistant HIV, the effectiveness of dolutegravir will also depend on the number of active antiretrovirals--HIV drugs to which the virus is not resistant--that can be combined with it.
Take Action:
  • Boycott Bill O'Reilly and FOX News and their advertisers. Bill discussed a French commercial by McDonalds that was meant to show that McDonalds is Gay Friendly. Bill said what is next? Is McDonalds going to be Al-Qaida friendly as well? Imagine - Bill O'Reilly compares Gays to Al-Qaida! Further, Boycott Fox's Owner "Rupert Murcoch" and get him thrown in jail for illegal - political donations, corruption, greed, bribery, hacking!
  • Boycott Target, Best Buy, Gold's Gym - for donating money towards anti-gay political candidates/organizations. Update: (12/26/2010): Target is continuing to donate to anti-gay groups/causes/politicians. Update 03/08/11 - Lady Gaga Ends Target Partnership, Reportedly Over Target's Poor LGBT Stance. Update 3/25/2010 - Target displays their hypocrisy and Sues California Gay Rights Group for Lobbying Outside Stores. Target is attempting to block the LGBT right of free speech! STOP SHOPPING AT TARGET!!!!!!!!!!!!!!!!! Update 4/8/2011: Target lost its case to stop the LGBT from canvassing in front of their stores. A huge PR Disaster for TARGET! Perhaps Target should go out of business as they betrayed their investers and customer base. Target contributed massive funds to a politician who would like to exterminate gays. Now, Target can not stop us from Boycotting them, nor picketing, nor talking to customers near their stores; although, Target allows a anti-gay company such as the Salvation Army to stand outside their door and speak with customers and raise money. Isn't this a double standard?
  • End DOMA (Defense of Marriage Act). Prevents Federal employees and Gays in the Military from gaining equal benefits. Prevents Gay Partners from gaining equal benefits.
  • Pass a LGBT friendly ENDA (Employee Non-Discrimination Act). ENDA would prevent employment discrimination of LGBT workforce.
  • Boycott Salvation Army as they will not hire Gays! "DO NOT DONATE TO THEM."
  • BOYCOTT "Chick-fil-a" for donating money to anti-gay groups.
  • BOYCOTT KOCH INDUSTRIES PRODUCTS- to include their products: Angel Soft toilet paper / Brawny paper towels / Dixie plates, bowls, napkins & cups / Mardi Gras napkins and towels / Quilted Northern toilet paper / Soft 'n Gentle toilet paper / Sparkle napkins / Vanity fair napkins / Zee napkins / Georgia-Pacific paper products & envelopes / All Georgia-Pacific lumber & building products (INVISTA Products) / Lycra / Stainmaster Carpet. The billionaire - Koch brothers are ultra republican - tea bag founders/supporters that do not support causes of the LGBT community.
  • Boycott WALMART - The National Gay and Lesbian Task Force criticized Wal-Mart for denying employee benefits to same-s-x partners and for failing to prohibit discrimination based on gender identity. By comparison, the group said two other chain stores with a strong presence in New York, Costco and Walgreens, did much better.
  • "Tune Out Trump", Boycott all Trump Hotel, casinos, holdings, The Apprentice and NBC Network! At CPAC, Trump said he is considering a run for president as a Republican. In a interview with the Des Moines Register, Trump added that he opposes all forms of legal recognition for gay couples, not just marriage. "They should not be able to marry," he said. So why does NBC keep the Apprentice when Donald Trump has stated he may run for president? After making racist remarks about Obama and recv'g public backlash, Trump decided not to run for president after NBC renewed his awful TV Show. How can NBC re-new the clown's show after he pulled such hateful shenanigans?
  • Boycott Georgia for Execution of Troy Davis @ 11:08 EST, Sep 21, 2011:
    Former US President and Former GA Gov. Jimmy Carter felt that TROY DAVIS should not be executed and deserved a re-trial. The Former Director of the FBI felt that TROY DAVIS Was Not Guilty! Do not drive through Goergia as it is dangerous. Do not fly via Atlanta. For your safety -Do not travel to GA. TELL YOUR COMPANY NOT TO PARTICIPATE IN A CONVENTION IN GA! "Georgia Executes Innocent People!"

And Now, Our War of the Fittest!

This group is called "Peckers Pics." The English - slang definition of "pecker" is to pluck at the truth. Therefore, we peck at items such as Gay Men's Health, Male Fitness, Gay (LGBT) Politics & Issues. In this section you may peck at each photo in order to decide the winner of the "war of the fittest!" Whereas, you should select the "Male Model" that may inspire you to exercise and "get fit!" Warning: This may stoke you!
Your participation in discussion of health / news articles - appearing in this message is greatly appreciated.
 
MICHAEL GSTOETTNER
 
VS
MAXIMILLIAN SILBERMAN
 
You Decide!
Maspalomas, Canary Islands Pride; May 14, 2011
Stoked?
Maspalomas, Canary Islands Pride; May 14, 2011
Gay Marriage Poll Touted by Mormons Seems Dubious
10/14/11 - Huffington Post - James Peron

Contrary to almost every other national poll regarding marriage equality, Deseret News, a newspaper owned by the Mormon Church, claims that two thirds of Americans oppose marriage equality.

When the mouthpiece of the Mormon Church publishes a new poll showing that two thirds of Americans now oppose marriage equality, it raises some questions. One needs to ask who conducted the poll, who was questioned, and whether respondents reflect the demographics of the national population. There is little such information in the article. All it or the attached graphics indicate is that 1,000 randomly chosen adults in 50 states were surveyed.

Did these people represent groups proportionally, or, as in a previous National Organization for Marriage poll, was it skewed toward older respondents? Deseret News doesn't say, nor do they reveal whether respondents reflect the population distribution of the states. For instance, a poll that over-surveys residents of the South will be skewed in one direction, while one that over-surveys residents of the Pacific states and New England would give very different results.

My office contacted the article's author, Micheal DeGroote, for details. He emailed, "The demographics are pretty standard for a national poll -- and I'm sure if you contacted Mr. Lawrence at Lawrence Research you could see the polling methodology was fine." DeGroote said the sticky point with critics would be the questions, not the demographics. I beg to differ.

Pollster Gary Lawrence responded to DeGroote's email by suggesting that I buy his book on Mormonism instead. He offered no information as to the demographics of his survey. For all I know, 90 percent of them were from Utah and 10 percent from the rest of the country. Without this information, the poll is valueless, except as political propaganda.

Besides omitting critical demographic data, other important information was left out, as well. For instance, who is Gary Lawrence?

Latter-Day Commentary describes him as an "LDS, Republican, conservative hawk" who was the "state LDS grassroots director for the Protect Marriage coalition. Brother Lawrence, who has served as a bishop has spent over 35 years studying opinions and behaviors of the American public."

In other words, this "pollster" was an official in the campaign that stripped same-sex Californians of their legal right to marry. Deseret News didn't see fit to report that Lawrence was not an unbiased pollster but rather a political propagandist for the Prop 8 campaign.

The Salt Lake Tribune, a paper not owned by the Mormon Church, reported that Lawrence was a key player in the Mormon-led anti-gay campaign. Lawrence, the paper wrote, "compared opponents of Prop 8 to those who sided with Lucifer against Jesus in the pre-mortal existence." (Pre-mortal existence is one of the Mormon doctrines that mainstream Christians reject.)

That comparison caused Lawrence's own son, Matthew, to resign from the Mormon Church and stop communications with his own family. Matthew said, "We can all agree to disagree and respect each other's informed opinions and decisions, but don't put me and Satan in the same sentence please."

As an organizer in the Prop 8 campaign, Lawrence told Mormons "to bear the price of printing various materials" themselves. If only 5,000 Mormons in the state spent $500 each on printing Prop 8 literature, that would hide an additional $2,500,000 in Mormon contributions. Mormon leaders told members to donate directly to the campaign, and various estimates of Mormon funding indicate that somewhere between 40 and 70 percent of all donations were made by Mormons, who are about 1 percent of the population. The Church also spent close to $200,000 on the campaign but reported their donations only after the election, contrary to state law.

Lawrence is a political propagandist who earned a pretty penny peddling anti-gay polls. He is also being paid by NOM and the right-wing Minnesota Family Council to produce poll results on their behalf. Minnesota Independent reported that "the groups touting the survey are remaining mum about the poll's details." Lawrence said that he can't release the data "purchased by an outside group." At least he didn't suggest they fork out $29.50 for his book on how Mormons can "improve their image, and spread the gospel."

I have a "confidential" copy of Lawrence's poll report that contains over 100 questions (located in full below). What is missing are details concerning respondent demographics. There is no information as to where these people live and whether they reflect the population of the country as a whole. Most of the questions are about how people perceive Mormons, with an emphasis on whether they would elect a Mormon as president. The questions ask about theology, as well, with questions on gay marriage wedged between gems such as, "If God held a televised news conference, would you watch it?" (Eleven percent would not -- probably because it would be aired on Fox.)

What demographic information is found indicates that this was not a representative sampling. For instance, 55 percent of Americans have some college education, but only 28 percent of respondents in the Lawrence survey do. Almost 40 percent of Americans aged 25 and over have a Bachelor's degree or Associate's degree; only 18 percent of the Lawrence respondents are college graduates. Reputable polls have consistently shown that the less education people have, the more anti-gay they tend to be.

An extensive poll by Gallup found that 39.8 percent of all Americans consider themselves conservative. According to data point #114 in the Lawrence poll, conservatives made up 51 percent of those surveyed (19 percent very conservative, 32 percent somewhat conservative).

Lawrence's poll doesn't reflect religious demographics, either. A Public Religion Research Institute survey found that "[n]early three-quarters of Catholics favor either allowing gay and lesbian people to marry (43%) or allowing them to form civil unions (31%). Only 22% of Catholics say there should be no legal recognition of a gay couple's relationship." The American Religious Identification Survey says the percentage of Catholics is 25 percent, but only 16 percent of those surveyed by Lawrence were Catholic.

Anti-gay evangelicals, on the other hand, were over-represented. According to Pew Forum, 26.3 percent of the public are members of evangelical churches, while 36 percent of respondents in the Lawrence poll were. Jewish respondents, who tend to be more pro-equality, were under-represented by half. Presbyterians, more supportive of gay rights than average, were 1 percent in the Lawrence survey, but ARIS says they are 2 percent of the population. Adherents to the anti-gay Assemblies of God were twice as prevalent in the Lawrence survey as in the population. Whereas ARIS says that membership in the fundamentalist Church of God is 0.3 percent of all Americans, Lawrence says that 2 percent of his respondents were members. Mormons make up just over 1 percent of the population, but 2 percent in the Lawrence survey. An over-representation of one percent is not significant unless repeated multiple times.

The ARIS survey says that 69.5 percent of Americans believe in a personal god, but 88 percent of respondents in the Lawrence survey do.
Other problems with the Lawrence poll include church attendance and age. In the Lawrence poll, 29 percent of respondents rarely or never attend church. Gallup says that 45 percent of Americans actually fit into this group. The Lawrence survey over-polls demographics more likely to be anti-gay, while under-polling those more likely to support equality of rights.

According to the U.S. Census, 72 percent of Americans are white, but 78 percent of Lawrence respondents are. He under-surveyed blacks, Latinos and Asians. Similarly, while Lawrence's "confidential" report indicates that 15 percent of respondents were age 55 to 64, their actual percentage in the population is much less: 8.6 percent. Only 12.4 percent of Americans are older than 65, but 17 percent of the participants in the Lawrence survey are.

These demographics indicate consistent bias in the Lawrence survey in a manner that distorts results in favor of political positions that Lawrence was well paid to promote.
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